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DeCS
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Descriptor English:
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Granulocyte-Macrophage Colony-Stimulating Factor
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Descriptor Spanish:
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Factor Estimulante de Colonias de Granulocitos y Macrófagos
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Descriptor Portuguese:
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Fator Estimulador de Colônias de Granulócitos e Macrófagos
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Synonyms English:
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CSF-GM
GM-CSF
Colony-Stimulating Factor, Granulocyte-Macrophage
Histamine-Producing Cell-Stimulating Factor
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Tree Number:
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D12.644.276.374.410.240.375
D12.776.395.240.300
D12.776.467.374.410.240.375
D23.529.374.410.240.375
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Definition English:
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An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. |
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Indexing Annotation English:
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DF: GMCSF
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See Related English:
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Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
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History Note English:
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91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91
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Allowable Qualifiers English:
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Record Number:
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28969
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Unique Identifier:
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D016178
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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